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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Regulatory B cells ： ウィキペディア英語版 Regulatory B cells Regulatory B cells (Bregs) represent a small population of B cells which participates in immunomodulations and in suppression of immune responses. These cells regulate the immune system by different mechanisms. The main mechanism is a production of anti-inflammatory cytokine interleukin 10 (IL-10). The regulatory effects of Bregs were described in various models of inflammation, autoimmune diseases, transplantation reactions and in anti-tumor immunity. ==History== In the 1970s it was noticed that Bregs could suppress immune reaction independently of antibody production. In 1996 Janeway´s group observed an immunomodulation of experimental autoimmune encephalomyelitis (EAE) by B cells. Similar results were shown in a model of chronic colitis one year later. Then a role of Bregs was found in many mouse models of autoimmune diseases as rheumatoid arthritis or systemic lupus erythematosus (SLE). 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Regulatory B cells」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.